FUW TRENDS IN SCIENCE & TECHNOLOGY JOURNAL

(A Peer Review Journal)
e–ISSN: 2408–5162; p–ISSN: 2048–5170

FUW TRENDS IN SCIENCE & TECHNOLOGY JOURNAL

MODELLING THE IMPACTS OF EFFECTIVE AND INEFFECTIVE TREATMENT TECHNIQUES IN CONTROLLING RELAPSE IN PATIENTS WITH PERSISTENT HBV DISEASE
Pages: 322-328
Nwaokolo, Martin Afam,; Nwaokolo Blessing


keywords: Treatment, relapse, chronic hepatitis B infection disease, reproduction number

Abstract

The effects of treatment strategies in controlling relapse in patients with ongoing HBV disease are analyzed. The reproduction number is obtained from which threshold values for treatment with and without relapse is acquired. The sensitivity analysis of the effective reproduction number uncovers that, transmission rate and the ratio without immunization advocated the disease flare-up. Mathematical experiments were carried out using MATLAB program, the outcome uncovers that patients adopting ineffective treatment systems are inclined to delay in fast reaction to treatment regimens, which thusly slow down the capability of recuperation from the infection. The epidemiological result of the key discoveries is that controlling the illness with an insufficient treatment methodology (self-medicine and visually impaired remedy) ought to be avoided to reduce the outcomes of drug resistance. Running against the norm, people that have embraced effective treatment strategies have shown more prominent possibilities for recuperation from the disease. Likewise, new medications with low obstruction ought to be given, that will assist with limiting the risk of reappearance of the infection because of drug resistance. Thus, a very much planned and satisfactorily carried out effective treatment strategy can significantly lessen the reproduction number, in this manner reducing relapse in patients with constant HBV disease.

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